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Testosterone for women in perimenopause and menopause

Dr. Zuleikha Tyebjee, MD, a board-certified family medicine physician, answers this in her recorded menopause masterclass. Every quote below is her exact wording, marked with where it appears in the recording.

What is testosterone used for in women?

“Testosterone is not FDA approved for these things. However, it is widely recommended by major societies to use for its primary use, which is going to be postmenopausal, hypoactive sexual desire disorder. Basically low libido, loss of sexual desire”

Dr. Ty, menopause masterclass · 16:47

“placebo-controlled meta-analyses have showed a significant improvement in sexual desire, arousal, the frequency, and the quality of orgasms, and reduction of sexually induced distress or related distress.”

Dr. Ty, menopause masterclass · 16:47

Topical testosterone versus pellets or injections

“The formulation of testosterone for women is going to be significantly lower than what men take.”

Dr. Ty, menopause masterclass · 17:54

“Data, again, leans towards topical testosterone, it recommends topical testosterone. It's better studied. It's got longer term data. It's also more consistent. Issues with injections and pellets is we tend to see these super highs and then these super lows.”

Dr. Ty, menopause masterclass · 18:58

Do you need labs on testosterone?

“testosterone is the only lab that we absolutely do need to monitor.”

Dr. Ty, menopause masterclass · 19:59

“And the main reason for that is really that we don't overshoot. So if we go too high in women with testosterone, the risk is that we get male symptoms. So facial hair, hair in places you don't want it, voice deepening, things that we want to avoid.”

Dr. Ty, menopause masterclass · 20:32

What side effects does Dr. Ty watch for?

“Biggest side effects that we see with topical testosterone certainly at the site of application. You'll have some irritation. Some women will develop like some transient or temporary skin changes, like some acne, … it usually goes away, but it's also something we can address if it happens.”

Dr. Ty, menopause masterclass · 21:06

“temporary or transient hair loss. Again, that typically resolves, but is also something we monitor closely. Otherwise, it's pretty darn well tolerated.”

Dr. Ty, menopause masterclass · 21:40

How should topical testosterone be applied?

“if you're applying testosterone to your upper buttocks or outer hip which is a great place to put it because you don't rub up against things”

Dr. Ty, menopause masterclass · 22:11

“So you wanna keep the areas symmetrical because again, we're keeping the same kind of skin and that's how testosterone would be absorbed consistently throughout the day.”

Dr. Ty, menopause masterclass · 22:44

Quotes are taken from the masterclass transcript; “…” marks where words were left out, and nothing was reworded. These pages provide general education, not an individual diagnosis or treatment plan.

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